Fabrication of modular hyaluronan-PEG hydrogels to support 3D cultures of Peptide Functionalized Gold Nanoparticles as a Stimuli Responsive Contrast
Stimuli-responsive conductive hydrogels have emerged as a new rising concept in the hydrogel research field due to their combined advantages of stimuli-responsivity and conductivity from conductive polymers (such as polyaniline, polypyrrole, and polythiophene), carbon nanomaterials (such as carbon nanotubes, graphene and graphene oxide), metals (such as Au and Ag), and conductive ionic compounds (such as Fe 3+ and Al 3+).
2021-03-02 · In addition to hydrogels responding to a single stimulus, dual-responsive hydrogels with enhanced gelation restrictions have been developed for drug delivery. Based on copolymerization of NIPAAm, PAA, and butyl acrylate (BA), a polymer with responsiveness to both temperature and pH was fabricated to deliver basic fibroblast growth factors (bFGFs) to infarcted rat myocardium. 51 51. The first part of the review highlights the high impact of stimuli-responsive hydrogels in materials science. From macro to micro scale, the review also collects the most recent studies on the preparation of hybrid polymeric microgels composed of a nanoparticle (able to respond to external stimuli), encapsulated or grown into a stimuli-responsive matrix (microgel). Hydrogels that Respond to Other Stimuli Hydrogels can be responsive to a vast array of other stimuli. Certain chemicals can be used as target molecules making the hydrogels either swell or degrade, either through direct interaction or indirectly through triggering an environmental change (e.g.
Hydrogels are swellable polymeric materials, and are being widely investigated as a carrier for drug delivery systems. Besides exhibiting swelling-controlled drug release, hydrogels also show stimuli responsive changes in their structural network and hence leading to the drug release. From this context, stimuli-responsive hydrogels are highly attractive as surrogate materials that can simulate dynamic physical microenvironments in vivo. Stimuli-responsive hydrogels formed by various natural and synthetic polymers are capable of showing distinctive changes in their properties with external stimuli like temperature, pH, light, ionic Notably, the hydrogels are highly sensitive to external stimuli, wherein gel–sol transition can be reversibly controlled by using temperature, pH and host–guest interaction. The integration of stimuli‐responsive supramolecular complexes and stimuli‐responsive biomolecular units as crosslinkers leads to hybrid hydrogels undergoing reversible triggered transitions across different stiffness states. Different applications of stimuli‐responsive biomolecule‐based hydrogels are discussed. From this context, stimuli-responsive hydrogels are highly attractive as surrogate materials that can simulate dynamic physical microenvironments in vivo.
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Collectively, recent breakthroughs in the design of stimuli‐responsive nanocomposite hydrogels improve their potential for operating as advanced systems in different biomedical applications that benefit from tailored single or multi‐responsiveness. Stimuli-Responsive Hydrogels This special issue on "Stimuli-Responsive Hydrogels", guest-edited by Prof.
Denna direkta sammansättning av stimuli-responsiva proteiner till hydrogeler rekombinant proteinbaserad ljuskänslig hydrogel genom kovalent montering av
Certain chemicals can be used as target molecules making the hydrogels either swell or degrade, either through direct interaction or indirectly through triggering … One strategy that has gained much attention in the last decades is the understanding and further mimicking of structures and behaviours found in nature, as inspiration to develop materials with additional functionalities. This review presents recent advances in stimuli-responsive gels with emphasis on functional hydrogels and microgels. Based on their responsiveness to external stimuli, the natural polymer-based hydrogels can be classified into the temperature-responsive hydrogel, pH-responsive hydrogel, light-responsive hydrogel, electricresponsive hydrogel, redox-responsive hydrogel, enzyme-responsive hydrogel, magnetic-responsive hydrogel, multi-responsive hydrogel, etc. Stimuli-Responsive Conductive Nanocomposite Hydrogels with High Stretchability, Self-Healing, Adhesiveness, and 3D Printability for Human Motion Sensing Zexing Deng Frontier Institute of Science and Technology, and State Key Laboratory for Mechanical Behavior of Materials, Xi’an Jiaotong University, Xi’an 710049, China Stimuli-responsive conductive hydrogel has been emerged as a new surging concept in hydrogel research field due to its combined advantages of stimuli-responsivity and conductivity from conductive 2019-11-15 2009-09-14 2021-03-02 2017-12-10 Stimuli-responsive materials, which exhibit changes in one or more properties in response to an external trigger, have gained interest due to their tunability and versatility.
Keywords: smart hydrogels, stimuli-responsive hydrogels, controlled release, drug delivery systems, anticancer drug delivery systems Introduction The first mention of hydrogels appeared in the literature at the beginning of the 19th century; they have been described as colloidal gels derived from inorganic salts. Fabrication of multi-stimuli responsive supramolecular hydrogels based on host–guest inclusion complexation of a tadpole-shaped cyclodextrin derivative with the azobenzene dimer † Xing Wang, ‡ a Juan Wang, ‡ a Yanyu Yang,ab Fei Yang ab and Decheng Wu *ab
Polyglycerol-based hydrogels from biodegradable raw materials were synthesized by crosslinking reactions of polyglycerol with citric and fatty acids. Three hydrogels were studied varying molar ratios of crosslinking agent.
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Recently, hydrogels and nanoparticles have been combined in advanced nanocomposite … 2018-06-07 The first part of the review highlights the high impact of stimuli-responsive hydrogels in materials science.
Stimuli-responsive hydrogels are capable of showing switchable sol-gel transition upon application of external triggers. The external stimuli including temperature, light, magnetic and electrical fields, and ultrasonic wave are considered physical triggers, while pH, redox reactions are considered chemical triggers [ 26 ]. Stimuli-responsive hydrogels have received great attention in cell biology and tissue engineering (TE) fields because of their capability to change their physical and chemical properties in response to user-defined stimuli, allowing modulation of cell microenvironment.
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17 Jun 2016 University of Hull | 06791 | P27 Stimuli-Responsive Hydrogels REEVE D'SOUZA © Kathy F. Atkinson.
The external stimuli including temperature, light, magnetic and electrical fields, and ultrasonic wave are considered physical triggers, while pH, redox reactions are considered chemical triggers [ 26 ]. Stimuli-responsive hydrogels have received great attention in cell biology and tissue engineering (TE) fields because of their capability to change their physical and chemical properties in response to user-defined stimuli, allowing modulation of cell microenvironment. Hydrogels are swellable polymeric materials, and are being widely investigated as a carrier for drug delivery systems. Besides exhibiting swelling-controlled drug release, hydrogels also show stimuli responsive changes in their structural network and hence leading to the drug release. From this context, stimuli-responsive hydrogels are highly attractive as surrogate materials that can simulate dynamic physical microenvironments in vivo.